Mers Cov Case Definition
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Middle east respiratory syndrome coronavirus mers cov case definition.
Mers cov case definition. Preamble the main goal of emerging respiratory virus surveillance is early detection of a case in canada and subsequently such virus surveillance informs efforts at containment and or mitigation of this novel respiratory pathogen. Middle east respiratory syndrome coronavirus mers cov. This document contains the case definitions for middle east respiratory syndrome coronavirus mers cov infection which is nationally notifiable within australia. The virus is distinct from both severe acute respiratory syndrome coronavirus sars cov and middle east respiratory syndrome coronavirus mers cov although closely related.
A case control study of hospitalized patients. Confirmed case laboratory confirmed mers cov infection through detection of viral nucleic acid or demonstration of seroconversion in 2 samples ideally taken 14 days apart. Al tawfiq ja hinedi k ghandour j khairalla h musleh s ujayli a et al. This definition should be used to determine whether a case should be notified.
Middle east respiratory syndrome mers is a viral respiratory infection of humans and dromedary camels which is caused by a coronavirus called middle east respiratory syndrome coronavirus mers cov. In late december 2019 investigation of a cluster of pneumonia cases of unknown origin in wuhan china resulted in identification of a novel coronavirus. A person with laboratory confirmation of mers cov infection 1 irrespective of clinical signs and symptoms. A person with an acute febrile respiratory illness of any severity an inconclusive mers cov laboratory test that is a positive screening test without confirmation and a direct epidemiologic link with a confirmed mers cov case.
At present positive serology mers cov specific antibodies results in the absence of pcr testing or sequencing are considered probable cases of mers cov infection if they meet the clinical case definition. A case with a positive pcr result for a single specific target without further testing but with a history of potential exposure and consistent clinical signs is considered a probable case. Albarrak am stephens gm hewson r memish za. Pneumonia or acute respiratory distress syndrome and.
Probable case a febrile acute respiratory illness with clinical radiological or histopathological evidence of pulmonary parenchymal disease e g. World health organization who revised interim case definition for reporting mers cov.